When it comes to managing estrogen levels during or after an anabolic steroid cycle, two of the most well-known aromatase inhibitors (AIs) are Aromasin (Exemestane) and Arimidex (Anastrozole). Both play a critical role in post-cycle therapy (PCT) and in-cycle estrogen control, but how do they really compare?
What Is Aromasin?
Aromasin, or Exemestane, is a steroidal aromatase inhibitor used to block the enzyme that converts androgens into estrogen. It’s considered a “suicidal” AI, meaning it binds irreversibly to the aromatase enzyme. This makes it effective even after discontinuation. You can buy pharmaceutical-grade Aromasin here.
What Is Arimidex?
Arimidex, or Anastrozole, is a non-steroidal AI commonly prescribed for estrogen control in breast cancer patients and by athletes during anabolic steroid cycles. It’s a reversible inhibitor, meaning it binds temporarily and loses effectiveness once discontinued.
Key Differences Between Aromasin and Arimidex
| Factor | Aromasin | Arimidex |
|---|---|---|
| Type | Steroidal AI (Suicidal) | Non-Steroidal AI (Reversible) |
| Half-Life | 24-27 hours | Around 48 hours |
| Estrogen Rebound Risk | Low | Moderate |
| Androgenic Effect | Mild | None |
| Suppression of Estrogen | Up to 85% | Up to 80% |
When to Use Each One?
If you’re running a strong bulking cycle with aromatizing compounds like testosterone enanthate or dianabol, Arimidex may provide faster estrogen suppression. On the other hand, Aromasin is a better option for preventing estrogen rebound during PCT, especially when combined with Clomid or Nolvadex.
Side Effects Comparison
Both compounds can lead to low estrogen if overdosed, causing joint pain, low libido, and fatigue. However, Arimidex is more likely to disrupt cholesterol levels. Aromasin, being mildly androgenic, may support a smoother transition into PCT with fewer lipid profile issues.
Stacking with Steroids
Both AIs are commonly used during cycles involving aromatizing steroids like:
For example, athletes stacking testosterone and dianabol often use Arimidex in-cycle, then switch to Aromasin for PCT control and recovery.
Which One Should You Choose?
It depends on your goal:
- During Cycle: Choose Arimidex for quick estrogen suppression.
- PCT or long-term control: Opt for a reliable Aromasin product from Dragon Pharma to minimize rebound and preserve your gains.
Final Thoughts
Both Aromasin and Arimidex have proven benefits depending on where you are in your cycle. Understanding their differences helps you make smarter choices, reduce risks, and improve recovery.
As always, pair your AI protocol with a solid post-cycle therapy plan. You can explore more in our guide: The 5 Most Popular Steroid Stacks and Cycles.